In a word: no. By the time the Tokugawa began to fail, more and more nobles began to like the idea of turning to the Emperor and Imperial Court to rule the country. The problem is no noble is gonna want one of their own to ruler over them. The Emperor, on the other hand, was the legal Head of State for Japan, so he was technically already reigning. By the time of the Meiji Restoration, the people and nobility by and large wanted to restore the Emperor, even if he ended up being a figurehead to the various Genro. No one was in any position to become Shogun.