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The Manhattan Project explored several technologies for acquiring fissile material, including several that never quite worked properly such as thermal diffusion and electromagnetic separation. However, one of the best technologies, centrifugal separation, was not explored by the Anglo-Commonwealth program. However, the Imperial Japanese Navy worked on centrifuge designs for its nuclear program, and they were seized at the end of the war. If successful, they would have been more advanced than the first historical ultra-centrifuges.

Given how important centrifuge technology has become in the nuclear and medical fields, what kind of changes would occur if the centrifuge had been more developed at the end of World War II? Would nuclear technology, medicine, genetics, etc. be more advanced?
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