The period between 1787 and 1815 was perhaps the most unstable period in American history due to the government being new and the people unsure of how it would be functioning alongside political divisions between federalism and anti-federalism. Your challenge is to have at least one state secede from the Union between 1787 and 1815 based on events and circumstances from OTL, preferably those that don't involve representation of slaves or abolishing the slave trade because that's been done to death and back.