Of course, as we all know Europe has been the “center” of the world for the past 200 or so years. What would it take for another region to dominate the world like Europe did? Establishing colonies, inventing the Scientific Method, starting the Industrial Revolution and an ATL Enlightenment etc etc.
The challenge is for atleast 200 years (in OTL, 1750-1950) of dominance of a non-European region by the world.
Preferably with a POD not earlier than 600 AD.