You would need a POD a long way back, which risks making the ACW being not as we know it. In particular, the fight over "bleeding Kansas" was a big part of the trigger for the ACW. Changing that could really affect the triggers for the ACW.
For a far back POD, say that the Missouri Compromise, say that the ATL Compromise Line is at Missouri's northern border rather than its southern, because *handwave*. That would turn Kansas into the fifth border state. That would at least make a secessionist Kansas a possibility in any *Civil War, albeit far from guaranteed.