The problem conservative Democrats faced in the 1920's is exemplified by their experience in 1928. Al Smith tried to convince middle- and upper-class voters that the Democrats would not interfere with the prosperity the US was enjoying under the Republicans. The Democratic platform even endorsed the protective tariff! If didn't work. As Newton Baker reflected after the election: "The results of this election make a fairly clear case against the Democratic Party's trying to be more Republican than the Republican Party. The Houston platform got us nowhere. As a matter of fact, I think it hurt us very badly, for in effect it was a concession that the Republicans had created and maintained the country's prosperity and that we...were going to try to do it the same way. Naturally the people who were voting on the prosperity plea would rather have experienced experts rather than amateurs do the job." Quoted in Allan J. Lichtman,
Prejudice and the Old Politics: The Presidential Election of 1928, p. 195.
https://books.google.com/books?id=KbGiJpDk6pwC&pg=PA195 Lichtman quotes Arthur Burns' s study of businessmen and the 1928 campaign: "Armed with inveterate convictions, the rank and file of the business community continued to cling to their shibboleths. Even the examples of their pecuniary idols--the Raskobs and the Du Ponts--left them undisturbed. They knew full well that men of big business venture occasionally on social and political experiments, but as merchants and dentists they could afford no such luxury."
This was not a new problem for conservative Democrats. In 1904, when the Democrats hoped to appeal to business by nominating the conservative Alton Parker,
the New York
Sun, the newspaper with closest ties to Wall Street, backed TR, writing: "We prefer the impulsive candidate of the party of conservatism to the conservative candidate of the party which the business interests regard as permanently and dangerously impulsive.."
https://books.google.com/books?id=X43uHzjM_GIC&pg=PA82
This is not necessarily to say that the Democrats would have been better off in the 1920's had they followed the Bryan-McAdoo strategy of appealing to pro-Prohibition, economically progressive farmers in the West and South. Those who advocated such a course pointed to the Wilson victory of 1916 which was made possible by the old Bryanite union of the South and West combined with labor support in states like Ohio. Conservative Democrats replied that 1916 was an aberration because of the peace issue; they looked backward to the Cleveland victories, which depended on winning northeastern states like New York, Connecticut, and New Jersey. Very likely neither strategy would have worked for the Democrats in 1924 or 1928 in the absence of some downturn in the economy.
Getting back to Republicans: Had James Wadsworth
https://en.wikipedia.org/wiki/James_Wolcott_Wadsworth_Jr. been re-elected to the US Senate in 1926, he might have led the anti-Prohibition forces in a serious (but probably unsuccessful) fight for the presidential nomination against Hoover. But Wadsworth had been defeated by Robert Wagner. Sr. who was of course equally "wet". The decisive vote was the 8.16% cast for the pro-Prohibition "independent Republican." F. W. Cristman.
https://en.wikipedia.org/wiki/1926_United_States_Senate_elections#New_York https://en.wikipedia.org/wiki/Franklin_W._Cristman Thus, even in New York state, it was not yet safe for a Republican to be a "wet."