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Pretty much what it says on the tin. With a POD of your choice, come up with a way for the Thylacine, aka Tasmanian Tiger, aka Tasmanian Wolf, aka Tassie, to get domesticated instead of going exinct. The degree of domestication could be anything from total (eg, dogs, assorted livestock, etc), to 'work in progress' (eg, various 'exotic' pets). As animals go, they were apparently very easy to tame, were successfully hand reared on at least one occasion, were kept as (apparently superiour) watch 'dogs' on multiple occasions, and were sort of cute, so I figure that given the right circumstances it's probably do-able.
Here's a picture for the benefit of anyone who doesn't know what a thylacine looks like: