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Your challenge, with a POD no earlier than 1806, is to devise, by all means possible, a way to stop the US from growing to strong to be effectively challenged by most major Latin American nations or the Spanish Empire.
The US must lose at least one major conflict to Spanish Imperial or Latin American forces
A Latin American country must be stronger than the US for a brief period of time, or even permanently if possible. Bonus points if said country is the Spanish Empire
This is not needed, but if possible, find a way for the Spanish Empire to outlive the British one
Weaken the Commonwealth realms and the Commonwealth itself as needed.