Firstly, nukes will have to be universally delayed somehow, the war can't go for that long with nukes in exsistance.
Secondly, Axis leaders become considerably more effective as war leaders. They take measures to increase their war production as early as possible and genuinely cooperate on strategy. As a result the Allies are pushed back much further than IOTL, but not knocked out.
Allied strategy becomes a Japan first one, and Japan is defeated in 1947. The allies then turn on Germany, but have no easy answers and rely on internal dissent and peripheral campiagns, but this is a slow process with no big decisive battles until 1955 when the SU re-enters the war and crosses the Volga into its former territory.