AH Challenge: Fragmented Canada

With a POD no earlier than 1917, would it be realistic for Canada ever to split up into separate nation states? I'm looking for something beyond the stereotypical WIs about Quebec seceding, so feel free to try to be inventive.

How would this effect the world, relations with the USA and the UK, etc.?
 
If Confederation only occured between Upper and Lower Canada, and even NB and NS stayed out, than it could have ended as a failure. Not terribly likely, but possible. A 20th c. POD with a balkanised Canada, though, is pretty much ASB.
 
How did Canada respond to the Great Depression? Could some kind of terrible mismanagement result in the destruction of Canada?
 
How did Canada respond to the Great Depression? Could some kind of terrible mismanagement result in the destruction of Canada?
Actually, the disaster of the Depression was why Newfoundland joined, as it was (no longer) viable on its own. Thus, rather than effecting fission it effected fusion.
 
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