Sorry for the old post. I hope that this doesnt cause too much trouble.
What about Rio Grande do Sul/Pampas, São Paulo, Zulia or Acre?
Well, for Rio Grande do Sul, as was said above, you need something going very bad for the Empire during the Regency Period, but after that is extremely unlikely.
São Paulo was in the core of the political Brazil. For an independent São Paulo you would need no Brazil at all. Maybe if the Braganzas had never fled to Rio in 1808 the Independence process would be so different that it would be possible.
Zulia? I think you mean the "Republica Juliana", no? It lasted only four months, they controlled just one city "Laguna", it was proclaimed not by the inhabitants of Santa Catarina but by the invaders of Rio Grande do Sul, and the rebells made everything possible to irritate the population instead of trying to have their support. Very unlikely.
An independent Acre in the middle of the Amazon would be something that would irritate both Brazil and Bolivia. Only if Galvez, the guy who proclaimed the independence, makes some agreement with a foreing potence, giving rights of exploration of nearly all country to American or British companies, and the USA or the UK decides to back them, and even it is doubtful.