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Hi!
According to Wikipedia, Admiral Chester Nimitz nearly lost his career due to an injury to his hand:
"Nimitz lost part of one finger in an accident with a diesel engine, only saving the rest of it—and his career—when the machine jammed against his Annapolis ring.[5]. He also suffered a severe ear infection, becoming partially deaf. He compensated by becoming proficient at reading lips[citation needed]. Nimitz barked orders even through the unbearable pain."
Suppose the injury is worse than IOTL and Nimitz is forced to leave the service between the wars. How does World War II unfold in the Pacific? Does MacArthur take over, and how would that change things?