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From the period to when Jaques Cartier first mapped out the entrance to the St-Lawrence water-way and claimed "Canada" for France in the early-mid 1500's, there was a period of about 60 years of stagnation before Samuel De Champlain set about creating an actual settlement and colony for France in Quebec.
What if a colony was set-up around the time of Cartier's last voyage in the 1540's? With the french having an established colony in North America about 60 years before the english and Jamestown?