Let's assume in this timeline, the United States assumes federal control over Liberia, rather than the American Colonization Society thrusting them into independence. Later in the Scramble for Africa, would we see the United States pursue more land, either in Guinea or elsewhere in Africa? I doubt they would have settler colonies like the UK did.
If the Spanish-American war still happens ITTL, might we see the United States try to annex some more African Colonies?