I think transhumanists are damn fools.IMO, that is the great folly of the transhumanists and, more broadly, of techno-utopians throughout history. They understood correctly that old ways of life would be rendered obsolete by new technology, but they never put much thought into what kinds of societies those systems would actually produce, instead assuming that it would just naturally lead to more freedom for people like them. In the case of the transhumanists, I find it odd that a small but vocal contingent of them is often quite hostile to LGBT rights, especially transgender rights, given that the technologies they embrace often flow naturally into transgender ideas about how your biological sex doesn't represent who you really are. The neoreactionary movement, specifically, was born from techno-libertarians on LessWrong, some of whom concluded that transhumanism could be used to reestablish their idealized feudalistic, hierarchical world and the traditional social mores that went with it, with a race of genetically-modified supermen serving as the new lords and kings. (Some cultural reactionaries, on the other hand, have recognized how transhumanism could fundamentally change society in ways they wouldn't like, and have taken a very Luddite approach to these technologies for this reason. Such arguments were made on Laura Ingraham's show, for instance, back in March.)
Hacker culture had the same mistake in failing to recognize how the internet would be abused for propaganda purposes, but that's a different subject.
Transhumanism might solve some problems, but it could create new ones.