It's doubtful that the Macedonian Empire could be brought up to Roman specs. The Romans built their Empire around sound communications - first the Med, then major rivers. Their road building was just icing on the cake.
Alexander was a great organiser-you don't build cities if you are not-he proved it in his conduct of war/s-some of his military innovations that are studied until today in military academies,are in the fields of Administration and Logistics.At his time,his first step in the west would be against Carthage and then of course Italy;Livy tries to tell us how difficult would be Italy for Alexander,but of course he hasn't convinced anyone as yet...
I would very much like to see a surviving Alexander turning West.It would be refreshing to see Carthage a...parking lot and Rome in ruins.Probably he would give the...ruins to Samnites.
Rome,despite what it appeared to be,had no geostrategic perspective;its general attitude to the world was defensive like,'once an enemy always an enemy' and if as a result the enemy was defeated,his lands were annexed.
The only clearly imperial move of Rome was the campaign of Agricola against Britain with what followed.Otherwise we fail to see in Rome any geostrategical notions dictating an imperial policy.