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IOTL, John, Prince of Asturias (b. 1478), the only son of Isabella I of Castille and Ferdinand II of Aragon, married in 1495 Margaret of Austria (b. 1480), daughter of Holy Roman Emperor Maximilian, before his death in 1498.

While reading this thread (https://www.alternatehistory.com/forum/threads/the-sforza-empress.278684/#post-17203036), I read that Maximilian tried to betroth Margaret to King Vladislaus II of Hungary in 1493. IOTL, the plans fell through, Vladislaus married Anne of Foix-Candale and Margaret married John. But if the plan with Vladislaus did work, then who else might have John been married to? Here are some possible candidates c. 1493-1495:

1. Catherine of York (https://en.wikipedia.org/wiki/Catherine_of_York) - the second youngest daughter of King Edward IV of England and Elizabeth Woodville, but the youngest available, as her younger sister, Bridget, was made a nun very early on. According to author Alison Weir, she was apparently considered as a bride for John. IOTL, she married William Courtenay, a supporter of Henry Tudor before he fell out of favour.

2. Joanna of Naples (https://en.wikipedia.org/wiki/Joanna_of_Naples_(1478–1518)) - only child of King Ferdinand I of Naples and Joanna of Aragon, Ferdinand of Aragon's sister, making her John's paternal first cousin. IOTL, she married her nephew, Ferdinand II of Naples, in 1496, but he died 2-3 months after the wedding without issue. Then Isabella of Castile recommended her as a bride for Henry VII Tudor after Elizabeth of York died in 1503, but the marriage never went through and Joanna never remarried.

3. Elisabeth of Bavaria (https://en.wikipedia.org/wiki/Elisabeth_of_Bavaria_(1478–1504)) - eldest daughter of George 'the Rich', Duke of Bavaria-Landshut. IOTL, became George's sole heir after the death of her brother, Ludwig, in 1496, and married her first cousin, Rupert of the Palatinate, in 1499. After George's death, for her children, the Duchy of Palatine-Neuburg was created.

4. Barbara Jagiellon of Poland-Lithuania (https://en.wikipedia.org/wiki/Barbara_Jagiellon) - youngest daughter of King Casimir IV of Poland-Lithuania (https://en.wikipedia.org/wiki/Casimir_IV_Jagiellon)

I considered adding Lucrezia Borgia, but then thought that an illegitimate daughter, even the illegitimate daughter of a Pope, wouldn't be a big enough catch.

Any thoughts? If John survives, what effects might a different marriage alliance have?

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