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Medici tree
Lorenzo de‘ Medici (1449-1492) married Clarice Orsini (1450-1488) in 1469
  1. Lucrezia Maria Romola de' Medici (b. 1470) married Jacopo Salviati (b. 1461) in 1486
  2. Twins who died after birth (March 1471)
  3. Piero di Lorenzo de' Medici (1472–1494), ruler of Florence married Alfonsina Orsini (b. 1472)
    1. Lorenzo di Piero de’ Medici (1492-1493)
    2. Clarice de‘ Medici (1493-1508) married Lorenzo Borgia (b. 1491) in 1505
  4. Maria Maddalena Romola de' Medici (b. 1473) married Cesare Borgia, Duke of Urbino (b. 1475) in 1489
    1. Maddalena (b.1490) married Alfonso d’Este, Duke of Ferrara (b. 1476) in 1505
    2. Lorenzo, Duke of Florence (b. 1491) married a) Clarice de’ Medici (1493-1509) in 1505 b) Beatrice Sforza (b. 1497) in 1512
    3. Alessandro, Duke of Urbino (b. 1493) married Eleonora d’Este (b. 1497)
    4. Lucrezia (b. 1496) married Ferdinand of Aragon, Prince of Taranto and Duke of Andria (b. 1488)
    5. Rodrigo (1498-1500)
  5. Contessina Beatrice de' Medici (1474)
  6. Giovanni di Lorenzo de' Medici (b. 1475) ascended to the papacy as Leo X in 1513
  7. Luisa de' Medici (1477–1488) engaged to Giovanni de' Medici il Popolano (1467-1498)
  8. Contessina Antonia Romola de' Medici (1478–1515) married Piero Ridolfi (1467–1525) in 1494
  9. Giuliano di Lorenzo de' Medici (1479–1496)
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