On 1532, King Henry would divorce Catherine of Aragon however, Clement VII would not accept the divorce and despite that he would marry Anne Boleyn and declare supremacy and split from the Catholic Church which would result in a daughter named Elizabeth of England in September 7, 1533, Henry would divorce and execute Anne Boleyn due to a crime she is rumored to commit in 1535 after the death of Queen Catherine of Aragon again and marry Jane Seymour who would give him another son named Edward, Prince of Wales born in October 12, 1537 and he would not have another child afterwards and and King Henry VIII would be content about the birth of a son, however the people brought in by Anne Boleyn would lead in Edward VI to be a protestant monarch, on 1542 in order to further the alliance between Spain and England and reconcile, Princess Mary is betrothed to Philip the Prince of Asturias and the marriage would happen on 1543 after a long time of choosing a marriage for the Princess, since he would use it to strengthen his son’s claims and even had his son betrothed to Joanna of Spain since it is no longer possible for him to marry Christina of Denmark and attempted to return his country to the Catholic fold due to the double match.
Henry VIII would die in 1548 leaving the throne to the 10-year-old Edward VI with protestant advisors which would lead England to the reformation and Edward V would be protestant himself, however Edward VI would die in 1553 after Henry VI died which would complicate the succession to the English throne since the next in line would be a Spanish one.