View attachment 354331
Francis I of France
The Two Ladies
After the treaty of the two ladies and the marriage in 1530, Anne of Savoy would give birth to two Princesses namely Marie b. May 2, 1533 and Eleonore b. June 4, 1538 adding two more daughters for Francis I aside from Louise, Charlotte, Madeleine and Margaret while the marriage of Maria of Portugal and Francis, Duke of Brittany would be deferred to 1535.
Catherine of Medici would be married to Antoine of Bourbon who wants the lands of Bourbon which are denied to them and Catherine of Medici is the ruler of the Auvergne and Boulogne inheritance in 1530, now that her aunt died without children, the marriage would secure the Bourbons of a possible bid for their lost inheritance.
In the meantime, Charles V and his wife Isabella of Portugal would have the following children:
Philip May 21, 1527
Maria, Holy Roman Empress June 21, 1528
Ferdinand b. d. November 22, 1529
Joanna June 26, 1535
John b. d. October 19, 1537
Alfonso April 21, 1539, Teutonic Knights, Priest
Isabella of Portugal would die on 1539 in Toledo shortly after the birth of her last son, Alfonso.