I'm not saying it wouldn't shorten the war but it would make the British about a shade lighter than the Nazis in the eyes of the world if that. And utterly destroy Europe.
It wouldn't utterly destroy Europe, western Europe may end up looking more like east and you may even have a few more Communist regimes coming up from the ruins if the British are too wary of basically guaranteed German retaliation with everything they've got, leaving the Soviets and La Resistance to twist the knife that the British inserted. Things would be grim, and the Allies would certainly be a shade darker but Randall Flagg isn't popping up any time soon.
I've actually got a scenario which involves an isolationist USA leaving a cash strapped UK and barrel scraping USSR in a stalemate with a Third Reich that's just hangin' on in Eastern Poland. The liberation of the Syrets concentration camp, further RAF photo evidence of the Holocaust and a stalemated Bagration lead the British down the road to Vegetarian and the 'N' plan. Had it in my head for a good few years now, got some help from a mate who does bio-chem as well but I've never quite managed to get it all out in a way that I like.