Regarding the power of the detonation - Most sources quote anywhere of 15-20 MEGATONS up to as high as 40 MEGATONS. Hiroshima was 15-20 KILOTONS.
Kiloton (Kt)- 1,000 tons
Megaton (Mt) -1,000,000 tons
The Tunguska Event was anywhere from 1,000 to 2,000 more powerful than Hiroshima. It probably detonated at 30 - 60K FT (1-2 km). 40Mt or larger weapons were only tested once. Even hardened Soviet designers were scared shitless by the ABOVE GROUND detonation's effect on the Earth's CRUST (it apparently left a dent).
As an example, a 20Kt weapon (aka Hiroshima bomb) will have 6 PSI of overpressure at about 0.9 miles (1.44 km) and a ONE megaton bomb will have the same power 3.2 miles (5.1 km). Multiply that by 15-40 times for Tunguska. 6 PSI will knock most building over like a house of cards.
The Federation of American Scientists has a very interesting blast effect simulator on their webside here:
http://www.fas.org/main/content.jsp?formAction=297&contentId=367
What happens if London is unlucky? A decent portion of Southern England is devestated (figure more or less total destruction by fire inside a 40 mile(64 km) circle, significant devestation over a somewhat larger area. The Government of the British Empire is decapitated, any member of the Royal family within a 20 - 25 mile radius of the IP is dead. The center of commerce for the world at the time disappears.
Talk about butterflies! Forget about WW I, start to figure out the short - medium impact on Humanity. Religions (start of the End Days?), politics (What happens to the Empire? The Raj? Scotland? Ireland?), economies (Lloyds of London, along with most of rest major underwriters, is GONE, along with all the records. Worldwide Depression sound like fun?).
This would have a greater impact on the Human Race than a decent percentage of the ASB threads. Interesting part is that this could have happened. Scary part is it WILL happen sooner or later, just a matter of when & where.
BTW: The famous Meteor Crater in Arizona was the result of a 3.6Mt event (of course that one hit the ground, which lessens the effect considerably).