That's why I'm asking for some PODs or events that could have led, prior to the first Protestant events, to a more enlightened approach by nobility and elite themselves.
I don't think you'll have a PoD that could both reverse deep tendencies of the time, and make nobility oblivious of its own interests at the point to support a radical religion.
I'm not sure what enlightened means in this context actually. It's certainly hard to reach in a context of religious crisis, where tolerance, libertinism, free-thinking (basically everything marking OTL Englightement) then even with a PoD.
If only one of these actually took place for some reason, it could have butterflied Reformation in first place, as it would have given background to another reglement of religious crisis of Late Middle Ages.
Elizabeth I, for instance, had a great chance to do many reforms in what concerns the topics cited in the first post, but due to the circumstances of the day, she had to act like any other conservative male king in power.
I fail to see why Elizabeth would have done that unless you mean she had the opportunity to do so, as any late medieval ruler had the opportunity to do so.
That the religious coexistance that she tried to impose was genuine or not isn't relevant : it was an actual policy because it fit her interest eventually (Nobody wanted to go trough an actual War of Religion, and going against Elizabeth too vehemently would have given room to Catholics)
She couldn't have went against the historical context and tendencies of its time, not without creating resistances even if they couldn't existed at first.
For instance.
- Antijudaism (rather than antisemitism that is rather a nationalist and/or racist stance rather than religious) of Luther was directly issued from medieval anti-judaism (especially in its post-Latran form) even if it was admittedly particularly insulting and violent. It was a feature of western Christianism and its violence was actually directly issued from the radicality of Reformation : that Jews didn't converted to Catholicism made sense, as it was Antichrist religion. But refusing to convert to the True Religion tm. showed that they were depraved.
- Political Misogynism
It's another direct legacy of late Middle-Ages, with the introduction of Roman Law trough Justinian's that had a clear bias against women. Given the spirit of european Renaissance, that literraly put everything Roman as the best, it would be hard to remove that from the historical context.
Maybe earlier events, dunno, a massive (and well succeded) European Peasant Revolt.
The problem with peasant revolts (Bagaudae, Jacquerie, Tuchinat, Great Rising, etc.) is that they tend to be spontaneous, epidermic and "headless". They had no program, no clear goal, etc. explaining why they were eventually used as scarecrows or manipulated by someone else that had the means to exploit their uprising.
Without a catastrophic collapse of late medieval or Renaissance society (something so big that it would probably compromise your OP), I don't see a peasant revolt "succeeding" (again, success is a bit hard to use there, as it implies objectives they didn't had).
In times where information took days, weeks or even months to arrive in its destination, probably we could only count on an absurd coincidence.
You really oversetimate the time an information used to travel. We're talking of a matter of days, maybe a week for anything between Rome and London by exemple.
Granted, in our age of information, it looks like prehistory, but "months" is inaccurate.
As I see I have much to learn yet.